T2* heterogeneity detected by CMR could be related to myocardial iron distribution in Thalassemia patients
نویسندگان
چکیده
منابع مشابه
Preferential patterns of myocardial iron deposition by multislice multiecho T2* CMR in thalassemia major patients
A. Meloni, V. Positano, A. Pepe, P. Pepe, M. C. Dell'Amico, C. Salvatori, P. Keilberg, G. Valeri, E. Cracolici, P. Bitti, A. Zuccarelli, M. F. Santarelli, and M. Lombardi MRI Lab, “G. Monasterio Foundation” and Institute of Clinical Physiology, CNR, Pisa, Italy, Azienda Ospedaliero-Universitaria Ospedali Riuniti "Umberto I-LancisiSalesi", Ancona, Italy, Policlinico "Paolo Giaccone", Palermo, It...
متن کاملSignificant improvement of survival by T2* CMR in thalassemia major
Background In 2004 seven Italian centers reported survival data for patients with thalassemia major (TM) and showed that heart disease due to iron overload was the most common cause of death (Borgna et al Haematologica 2004). In the same years the accurate and noninvasive assessment of cardiac siderosis was made possible in Italy by the introduction of the T2* cardiovascular magnetic resonance ...
متن کاملBlack-blood T2* technique for myocardial iron measurement in thalassemia.
PURPOSE To compare the effectiveness and reproducibility of a new black-blood sequence vs. a conventional bright-blood gradient-echo T2* sequence for myocardial iron overload measurement in thalassemia. MATERIALS AND METHODS Twenty thalassemia patients were studied. Black-blood sequence images were acquired in diastole after a double inversion recovery (DIR) preparation pulse. Bright-blood se...
متن کاملAn automatic method for myocardial T2* curve fitting in thalassemia patients with severe iron overload
Background Myocardial iron overload assessment by multislice multiecho T2* technique is used in the clinical management of thalassemia major (TM) patients. Signal decay curves are extracted from the 16 left ventricular (LV) segments and the fitting of these curves to a mono-exponential model provides the corresponding T2* values. In patients with severe cardiac iron overload, where signal will ...
متن کاملCorrelation between Heart and Liver Iron Levels Measured by MRI T2* and Serum Ferritin in Patients with β-thalassemia Major
Background Transfusion-induced iron overload leads to many complications in patients with β-thalassemia major. This study aimed to compare the level of iron stored in the liver and heart measured by MRI T2 * with ferritin levels in these patients. Materials and Methods This study was done on 52 patients with β-thalassemia major aged 7 to 29 years. Serum ferritin level was checked and heart and ...
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ژورنال
عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance
سال: 2009
ISSN: 1532-429X
DOI: 10.1186/1532-429x-11-s1-p134